Clinical Case Reports for the Evidence-Based Era

As defined, erectile dysfunction (ED, erectile dysfunction) is the persistent inability to achieve and/or maintain an erection sufficient for satisfactory sexual activity (symptoms must persist for a minimum of three months, unless ED is associated with trauma or surgery surgery). It is estimated that 3 million men in Poland are affected, and in a population with cardiovascular disease (CVD, or Cardiovascular Disease) it affects nearly 80% of patients.

The use of dose-dense or "dense-dose" complementary chemotherapy in early breast cancer has allowed significantly improve the four-year disease-free survival (DFS) rate, especially in a group of patients who are young and have the so-called triple-negative (tripple nega􀆟ve) breast cancer phenotype. This mode of administration of chemotherapy is associated with a significantly higher (about 20%) risk of neutropenic fever (GN). As part of primary prophylaxis, current standards use granulocyte colony-stimulating agents granulocyte colony-stimulating agents, mainly the long-acting form - pegfilgrastim. Recently, a new long-acting G-CSF - lipegfilgrastim.

Rare disease affects less than 1 person/2000 population. To date, 6,000 rare diseases have been detected. Each person is a carrier of 5-10 genes for rare diseases (mostly recessive genes). The rarity of of these diseases usually leads to a delay in making a correct diagnosis, sometimes by many years.

Mycoplasma pneumoniae is the agent e􀆟ologiczny of 40% of out-of-hospital pneumonia in children. The infection most often involves the respiratory tract, some patients have symptoms from other organs and systems, including autoimmune hemolytic anemia with cold agglutinins.