Clinical Case Reports for the Evidence-Based Era

In recent years, the number of refugees and illegal immigrants reaching Europe from the many regions affected by warfare, humanitarian disasters, and epidemics. Along with the changing directions from which refugees are arriving, the potential epidemiological risks are also changing and new health challenges arise at the ED level as well as in the context of population health. A particularly dangerous trend can be seen in the potential reduction in travel time from an endemic country to Europe, of people who are healthy carriers of potentially infectious diseases, which allows the development of the full-blown forms of particular entities only in destination countries, where people working in the in the health sector do not have adequate training to deal with diseases that are new to their territory with diseases. The presentation presents two case reports with similar symptomatology but completely different etiology and management using P.falciparum malaria and Ebola hemorrhagic fever as examples.

Esophageal overgrowth is a rare congenital defect that still poses a challenge to the surgeon. Among the types of overgrowth, the most common is type III, characterized by the presence of an esophageal-tracheal fistula from the lower segment. The procedure involves closing the fistula and then anastomosing the two overgrown sections. In some cases, complications develop, among which the most common are esophageal stricture at the anastomosis site, leakage at the anastomosis site, and recurrence of esophageal-tracheal fistula. Case report: The authors present a description of the diagnosis and treatment of a girl operated on for esophageal overgrowth t. III, who developed a large tracheal diverticulum and recurrence of esophagotracheal fistula. The choice was unusual surgical access through the left pleural cavity using a thoracoscopic technique.

The significant risk of permanent impairment in frostbite, such as the loss of fingers, challenges doctors and prompts them to use all available therapeutic options to avoid or reduce disability. At the same time, doctors' average practical knowledge of frostbite is archaic and anecdotal. To date, the practice of treating third- and fourth-degree frostbite boils down to diagnosis, desmurgery and surgical treatment - amputation. It is extremely rare for patients to be referred to specialized units for reconstructive surgery. Meanwhile, techniques using stapled and free flaps often allow to reduce the level of amputation and reduce the degree of disability.

A new era in reconstructive transplantation, has introduced vascularized allogeneic composite grafts, such as the human face, hand, larynx and abdominal wall. Currently, 38 face transplants have been performed worldwide with an 85% survival rate. Routine face transplantation is limited due to the need to take immunosuppressive drugs with which serious complications are associated, up to and including death.