Clinical Case Reports for the Evidence-Based Era

Emphysematous pyelonephri􀆟s (EPN) is an acute complication of urinary tract infection with bacteria that produce gas. The mortality rate in this condition, according to some authors, can be as high as 80%. The most common pathogen causing EPN is Escherichia coli. Therapy is based on empirical administration of antibiotics and surgical treatment.

The study included 72 women who had miscarriages and were diagnosed with the latent form of toxoplasmosis in combination with with human papillomavirus (HPV) and Epstein-Barr virus (EBV) infection. The study found was the absence of clinical signs of infection with positive polymerase chain reaction (PCR) results for the presence of HPV and EBV genetic material. The latent form of HPV infection in combination with EBV infection and toxoplasmosis is more often characterized by a high levels of HPV types: 16, 31, 35, 52, 56, 58, 59 in the urogenital smear, low IgG avidity to T. gondii and a high content of ЕBV in saliva. Only 2 of the 72 women tested had spontaneous regression of HPV within a year. In order to reliably predict oncogenic risk and exclude manifest infection, long-term prospective follow-up. In order to determine the exact cause of miscarriages in women with latent toxoplasmosis combined with infection- EBV and HPV infection, it is necessary to use PCR testing from stillbirth tissues.

Among patients qualified for surgery, especially with gastrointestinal pathology, the percentage of malnourished reaches 60%. Preparation of the patient before surgery should be comprehensive and include optimization of nutritional status.

Amniotic fluid embolism (AME) is a rare complication of pregnancy, unpredictable, with a varied clinical picture clinical picture, with dangerous consequences for mother and newborn. PE is the cause of 20% of perinatal maternal deaths [1]. Embolism is caused by amniotic fluid entering the mother's circulation. The authors of describe the case of a 21-year-old female patient who was diagnosed with amniotic fluid embolism. The newborn, who was born at 35 weeks' gestation, by natural means with a birth weight of 2620 g, with APGAR scores: 0-2-5-6-7 points at 1-3-5-10-15 minutes of life respectively, with symptoms of perinatal hypoxia, survived. His mother suffered a severe complication of ischemic stroke with hemiplegia.