Clinical Case Reports for the Evidence-Based Era

Acute ischemia is a sudden drop in blood perfusion in a limb causing a potential threat to the viability of the limb. The 30-day amputation rate due to acute ischemia is 10% to 30%, with a mortality rate of 15-20%. For several years, in addition to surgical methods, we have had the option of endovascular treatment of of acute ischemia. The methods used: targeted pharmacological thrombolysis, percutaneous aspiration thrombectomy, percutaneous mechanical thrombectomy and various combinations of these procedures.

Multi-organ injuries are the third most common cause of death in Poland, and are also the leading cause of death in people under the age of 40. Among surviving patients, up to 40% of the cases of multi-organ injury multi-organ injury is the cause of permanent disability.

Congenital diaphragmatic hernia (CDH) is a malformation involving the displacement of viscera into the thoracic region through a pathological opening in the diaphragm, resulting from its abnormal development.

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome resulting from an exaggerated inflammatory reaction. HLH can be triggered by a variety of congenital and acquired factors. The most common symptoms of HLH are persistent fever, splenic enlargement and cytopenias in the peripheral blood. Laboratory findings include hyperferritinemia (often >10000 μg/L) and elevated levels of soluble receptor for interleukin-2. Without appropriate treatment, HLH leads usually to the death of the patient.