Clinical Case Reports for the Evidence-Based Era

Kidney cancer accounts for about 3% of all malignant tumors. It mainly affects patients 60-70 years old, more often men than women. The mainstay of treatment is nephrectomy, and renal artery embolization is used as palliative therapy. Combined treatment uses immunotherapy and modern targeted therapy.

Cystadenocarcinoma is a rare malignant liver tumor that arises de novo or from benign lesions of the nature of cystadenocarcinomas. Symptoms are nonspecific and include: pain in the right upper quadrant of the abdominal cavity, a feeling of discomfort or fullness, jaundice, weight loss and are related related to the size of the lesion. The recommended treatment is resection of the lesion along with a margin of healthy tissue.

One of the indications for liver transplantation is primary malignancies. Among adults, the most common is hepatocellular carcinoma, while among children embryonal hepatoma predominates. In addition, it has been noted the existence of tumors with intermediate characteristics between the two.

In HPV infections, a very important and underestimated clinical aspect is the co-occurrence of lesions in different locations and the ease of transmission between sexual partners. Also of significant clinical importance is vertical infection during pregnancy, which can lead to infection of the fetus. Virus-induced papillomas can develop in any part of the upper and lower respiratory tract as well as in the upper gastrointestinal tract. They most often occupy the larynx, and also develop in the tonsils, trachea, bronchi and lungs, and can also show aggressive growth and undergo malignant transformation.