Clinical Case Reports for the Evidence-Based Era

Diabetic foot complicated by ulcer infection is one of the most common problems associated with diabetes. The clinical symptoms accompanying the infection are mostly poor, leading to a delay in correct diagnosis. As a result, unfortunately, there are still often in patients to amputation of a limb. The clinical case presented here, a 73-year-old patient with multiple concomitant diseases, is an example of how, through appropriate treatment of an infection first assessed as an indication for amputation, this could have been avoided. The use of appropriate antibiotic therapy based on clinical assessment of the wound, swab results, and the patient's general condition, along with systematic wound debridement, formed the basis for therapeutic success. A number of diagnostic tests, such as imaging of the foot (X-ray), vascular status (pulse evaluation, ultrasound Doppler), laboratory (including deep wound cultures, inflammatory indicators). Since this problem affects many medical fields, it is important to cooperate between specialists in the diagnosis and treatment of this condition.

Thyroid-associated orbitopathy (TAO) is a syndrome of ocular symptoms ocular symptoms caused by autoimmune inflammation of the soft tissues of the orbit leading to temporary or permanent damage to the organ of vision. It usually accompanies hyperthyroidism, but does not exclude the existence of hypothyroidism.

The purpose of this study is to describe the case of a patient with end-stage renal failure who underwent radiotherapy of the abdominal fields in childhood. The results and treatment history are analyzed. The patient was diagnosed with an abdominal tumor at age 1 (1967). Treatment was applied surgery and radiation therapy. At age 25 (1992), she was diagnosed with type 2 diabetes, despite no history of risk factors for the development of this disease. Seven years later (2000) gastrointestinal obstruction caused by adhesions (a probable result of radiation therapy). At that time, a right kidney tumor and left kidney cirrhosis were suspected. In 2008, progressive tumor growth in the right kidney was confirmed. Two years later (2010) The right kidney was removed. Histopathological diagnosis showed clear cell carcinoma. On the third day after surgery, renal replacement therapy (hemodialysis) was started. Currently, dialysis therapy is continued, and the patient is awaiting qualification for transplantation. Conclusions: Based on the analysis, it was concluded that the health problems found in the patient may have been a consequence of radiation therapy in childhood. Very difficult to determine to what extent radiation contributed to the pathology.