Clinical Case Reports for the Evidence-Based Era

Renal failure occurs in about one-third of patients with acute heart failure and in about 25-40% of patients with chronic heart failure. Damage to one of these organs can secondarily lead to abnormal function of the other, which underlies the pathophysiology of CRS cardiac-renal syndrome.

Diabetic foot complicated by ulcer infection is one of the most common problems associated with diabetes. The clinical symptoms accompanying the infection are mostly poor, leading to a delay in correct diagnosis. As a result, unfortunately, there are still often in patients to amputation of a limb. The clinical case presented here, a 73-year-old patient with multiple concomitant diseases, is an example of how, through appropriate treatment of an infection first assessed as an indication for amputation, this could have been avoided. The use of appropriate antibiotic therapy based on clinical assessment of the wound, swab results, and the patient's general condition, along with systematic wound debridement, formed the basis for therapeutic success. A number of diagnostic tests, such as imaging of the foot (X-ray), vascular status (pulse evaluation, ultrasound Doppler), laboratory (including deep wound cultures, inflammatory indicators). Since this problem affects many medical fields, it is important to cooperate between specialists in the diagnosis and treatment of this condition.

Thyroid-associated orbitopathy (TAO) is a syndrome of ocular symptoms ocular symptoms caused by autoimmune inflammation of the soft tissues of the orbit leading to temporary or permanent damage to the organ of vision. It usually accompanies hyperthyroidism, but does not exclude the existence of hypothyroidism.